Reconstituted Complex

An interaction is detected between purified proteins in vitro.

Publication

Identification and validation of novel spinophilin-associated proteins in rodent striatum using an enhanced ex vivo shotgun proteomics approach.

Baucum AJ, Jalan-Sakrikar N, Jiao Y, Gustin RM, Carmody LC, Tabb DL, Ham AJ, Colbran RJ

Spinophilin regulates excitatory postsynaptic function and morphology during development by virtue of its interactions with filamentous actin, protein phosphatase 1, and a plethora of additional signaling proteins. To provide insight into the roles of spinophilin in mature brain, we characterized the spinophilin interactome in subcellular fractions solubilized from adult rodent striatum by using a shotgun proteomics approach to identify proteins ... [more]

Mol. Cell Proteomics Jun. 01, 2010; 9(6);1243-59 [Pubmed: 20124353]

Throughput

  • Low Throughput

Curated By

  • BioGRID