BAIT
PPP1R9B
Neb2
protein phosphatase 1, regulatory subunit 9B
GO Process (9)
GO Function (1)
GO Component (8)
Gene Ontology Biological Process
- actin filament organization [ISO]
- calcium-mediated signaling [ISO]
- cell migration [ISO, ISS]
- cellular response to morphine [ISO, ISS]
- dendrite development [ISO]
- filopodium assembly [ISO, ISS]
- negative regulation of cell growth [ISO]
- regulation of opioid receptor signaling pathway [ISO, ISS]
- regulation of protein phosphorylation [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
MYH10
MCH-B, NMMHC-B, SMemb
myosin, heavy chain 10, non-muscle
GO Process (28)
GO Function (6)
GO Component (21)
Gene Ontology Biological Process
- ATP catabolic process [ISO]
- actin cytoskeleton organization [ISO]
- actin filament-based movement [ISO]
- actomyosin structure organization [ISO]
- adult heart development [ISO]
- axon guidance [ISO]
- axonogenesis [ISO]
- brain development [ISO]
- cardiac myofibril assembly [ISO]
- cell proliferation [ISO]
- cellular component movement [NAS]
- cerebellar Purkinje cell layer development [ISO]
- exocytosis [ISO]
- fourth ventricle development [ISO]
- in utero embryonic development [ISO]
- lateral ventricle development [ISO]
- mitotic cytokinesis [ISO]
- myofibril assembly [ISO]
- neuromuscular process controlling balance [ISO]
- neuron migration [ISO]
- neuron projection development [ISO]
- nuclear migration [ISO]
- plasma membrane repair [ISO]
- regulation of cell shape [ISO]
- retina development in camera-type eye [ISO]
- substrate-dependent cell migration, cell extension [ISO]
- third ventricle development [ISO]
- ventricular cardiac muscle cell development [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- actin cytoskeleton [ISO]
- actomyosin [ISO]
- axon [ISO]
- cell cortex [ISO]
- cleavage furrow [ISO]
- cytoplasm [ISO]
- dendritic spine [ISO]
- extracellular vesicular exosome [ISO]
- growth cone [ISO]
- midbody [ISO]
- mitochondrion [ISO]
- myosin II complex [ISO]
- myosin II filament [ISO]
- myosin complex [ISO]
- neuromuscular junction [ISO]
- neuron projection [ISO]
- neuronal cell body [ISO]
- nucleus [ISO]
- plasma membrane [ISO]
- spindle [ISO]
- stress fiber [ISO]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification and validation of novel spinophilin-associated proteins in rodent striatum using an enhanced ex vivo shotgun proteomics approach.
Spinophilin regulates excitatory postsynaptic function and morphology during development by virtue of its interactions with filamentous actin, protein phosphatase 1, and a plethora of additional signaling proteins. To provide insight into the roles of spinophilin in mature brain, we characterized the spinophilin interactome in subcellular fractions solubilized from adult rodent striatum by using a shotgun proteomics approach to identify proteins ... [more]
Mol. Cell Proteomics Jun. 01, 2010; 9(6);1243-59 [Pubmed: 20124353]
Throughput
- Low Throughput
Curated By
- BioGRID