BAIT
PPP1R9B
Neb2
protein phosphatase 1, regulatory subunit 9B
GO Process (9)
GO Function (1)
GO Component (8)
Gene Ontology Biological Process
- actin filament organization [ISO]
- calcium-mediated signaling [ISO]
- cell migration [ISO, ISS]
- cellular response to morphine [ISO, ISS]
- dendrite development [ISO]
- filopodium assembly [ISO, ISS]
- negative regulation of cell growth [ISO]
- regulation of opioid receptor signaling pathway [ISO, ISS]
- regulation of protein phosphorylation [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
ACTB
Actx
actin, beta
GO Process (7)
GO Function (8)
GO Component (16)
Gene Ontology Biological Process
Gene Ontology Molecular Function- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II distal enhancer sequence-specific DNA binding [ISO]
- Tat protein binding [ISO]
- kinesin binding [ISO]
- nitric-oxide synthase binding [ISO]
- nucleosomal DNA binding [ISO]
- protein binding [IPI]
- protein kinase binding [IPI]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [ISO]
- RNA polymerase II distal enhancer sequence-specific DNA binding [ISO]
- Tat protein binding [ISO]
- kinesin binding [ISO]
- nitric-oxide synthase binding [ISO]
- nucleosomal DNA binding [ISO]
- protein binding [IPI]
- protein kinase binding [IPI]
Gene Ontology Cellular Component
- MLL5-L complex [ISO]
- NuA4 histone acetyltransferase complex [ISO]
- axon [IDA]
- blood microparticle [ISO]
- cortical cytoskeleton [ISO]
- cytoplasmic ribonucleoprotein granule [ISO]
- cytosol [ISO, TAS]
- extracellular space [ISO]
- extracellular vesicular exosome [ISO]
- focal adhesion [ISO]
- membrane [ISO]
- myelin sheath [ISO]
- nuclear chromatin [ISO]
- postsynaptic density [IDA]
- protein complex [IDA, ISO]
- ribonucleoprotein complex [ISO]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Identification and validation of novel spinophilin-associated proteins in rodent striatum using an enhanced ex vivo shotgun proteomics approach.
Spinophilin regulates excitatory postsynaptic function and morphology during development by virtue of its interactions with filamentous actin, protein phosphatase 1, and a plethora of additional signaling proteins. To provide insight into the roles of spinophilin in mature brain, we characterized the spinophilin interactome in subcellular fractions solubilized from adult rodent striatum by using a shotgun proteomics approach to identify proteins ... [more]
Mol. Cell Proteomics Jun. 01, 2010; 9(6);1243-59 [Pubmed: 20124353]
Throughput
- Low Throughput
Curated By
- BioGRID