BAIT

NSP7AB

nsp7, sars1ab, orf1ab, SARS-CoV nsp7ab, SARS-CoV nsp7, SARS-CoV sars1ab, orf1ab-nsp7, orf1ab-nsp7ab, pp1ab, R1AB_CVHSA, PRO_0000037314, SARS-CoV-1ab-nsp7ab
Non-structural protein 7; nsp7
COVID-19 Coronavirus Project
GO Process (0)
GO Function (0)
GO Component (0)
Severe acute respiratory syndrome coronavirus
PREY

NSP2AB

nsp2, sars1ab, orf1ab, SARS-CoV nsp2ab, SARS-CoV nsp2, SARS-CoV sars1ab, orf1ab-nsp2, orf1ab-nsp2ab, pp1ab, p65 homolog, R1AB_CVHSA, PRO_0000037310, SARS-CoV-1ab-nsp2ab
Non-structural protein 2; nsp2; p65 homolog
COVID-19 Coronavirus Project
GO Process (0)
GO Function (0)
GO Component (0)
Severe acute respiratory syndrome coronavirus

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Genome-wide analysis of protein-protein interactions and involvement of viral proteins in SARS-CoV replication.

Pan J, Peng X, Gao Y, Li Z, Lu X, Chen Y, Ishaq M, Liu D, Dediego ML, Enjuanes L, Guo D

Analyses of viral protein-protein interactions are an important step to understand viral protein functions and their underlying molecular mechanisms. In this study, we adopted a mammalian two-hybrid system to screen the genome-wide intraviral protein-protein interactions of SARS coronavirus (SARS-CoV) and therefrom revealed a number of novel interactions which could be partly confirmed by in vitro biochemical assays. Three pairs of ... [more]

PLoS ONE Oct. 01, 2008; 3(10);e3299 [Pubmed: 18827877]

Throughput

  • Low Throughput

Curated By

  • BioGRID