BAIT
ITGB2
2E6, AI528527, Cd18, LAD, LCAMB, Lfa1, MF17
integrin beta 2
GO Process (18)
GO Function (7)
GO Component (8)
Gene Ontology Biological Process
- activated T cell proliferation [IMP]
- cell adhesion [IGI, IMP]
- cell-matrix adhesion [ISO]
- cellular extravasation [IMP, ISO]
- endothelial cell migration [ISO]
- heterotypic cell-cell adhesion [ISO]
- integrin-mediated signaling pathway [IDA]
- leukocyte cell-cell adhesion [ISO]
- leukocyte migration involved in inflammatory response [ISO]
- natural killer cell activation [ISO]
- neutrophil chemotaxis [IMP, ISO]
- positive regulation of NF-kappaB transcription factor activity [ISO]
- positive regulation of angiogenesis [ISO]
- positive regulation of nitric oxide biosynthetic process [ISO]
- receptor clustering [ISO]
- regulation of peptidyl-tyrosine phosphorylation [ISO]
- signal transduction [ISO]
- single organismal cell-cell adhesion [IGI, ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
MAP1B
A230055D22, AI843217, LC1, MAP5, Mtap-5, Mtap1b, Mtap5
microtubule-associated protein 1B
GO Process (13)
GO Function (6)
GO Component (16)
Gene Ontology Biological Process
- axon extension [IMP]
- axonogenesis [IGI]
- cellular process [ISO]
- dendrite development [IMP]
- establishment of monopolar cell polarity [IMP]
- microtubule bundle formation [IMP, ISO]
- microtubule-based process [TAS]
- mitochondrion transport along microtubule [IMP]
- negative regulation of intracellular transport [IMP]
- negative regulation of microtubule depolymerization [ISO]
- positive regulation of axon extension [IMP, ISO]
- positive regulation of microtubule polymerization [ISO]
- positive regulation of neuron differentiation [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- axon [ISO]
- cell [IMP]
- cytoplasm [ISO]
- cytoskeleton [ISO]
- cytosol [IDA]
- dendrite [ISO]
- growth cone [ISO]
- intracellular [IMP]
- microtubule associated complex [ISO, TAS]
- neuronal cell body [ISO]
- neuronal postsynaptic density [IDA]
- perikaryon [ISO]
- perinuclear region of cytoplasm [ISO]
- photoreceptor outer segment [IDA]
- plasma membrane [ISO]
- postsynaptic density [IDA, ISO]
Mus musculus
Reconstituted Complex
An interaction is detected between purified proteins in vitro.
Publication
LCP1 preferentially binds clasped ?M?2 integrin and attenuates leukocyte adhesion under flow.
Integrins are ?/? heterodimers that interconvert between inactive and active states. In the active state the ?/? cytoplasmic domains recruit integrin-activating proteins and separate the transmembrane and cytoplasmic (TMcyto) domains (unclasped TMcyto). Conversely, in the inactive state the ?/? TMcyto domains bind integrin-inactivating proteins, resulting in the association of the TMcyto domains (clasped TMcyto). Here, we report the isolation of ... [more]
J. Cell. Sci. Dec. 21, 2017; 131(22); [Pubmed: 30333137]
Throughput
- High Throughput
Curated By
- BioGRID