BAIT

MYP2

myo3, SPAC4A8.05c
myosin II heavy chain Myo3
GO Process (3)
GO Function (1)
GO Component (3)
Schizosaccharomyces pombe (972h)
PREY

CDC11

SPCC1739.11c
SIN component scaffold protein, centriolin ortholog Cdc11
GO Process (4)
GO Function (2)
GO Component (4)
Schizosaccharomyces pombe (972h)

Synthetic Growth Defect

A genetic interaction is inferred when mutations in separate genes, each of which alone causes a minimal phenotype, result in a significant growth defect under a given condition when combined in the same cell.

Publication

Distinct Roles of Myosin-II Isoforms in Cytokinesis under Normal and Stressed Conditions.

Okada H, Wloka C, Wu JQ, Bi E

To address the question of why more than one myosin-II isoform is expressed in a single cell to drive cytokinesis, we analyzed the roles of the myosin-II isoforms, Myo2 and Myp2, of the fission yeast Schizosaccharomyces pombe, in cytokinesis under normal and stressed conditions. We found that Myp2 controls the disassembly, stability, and constriction initiation of the Myo2 ring in ... [more]

iScience Apr. 26, 2019; 14();69-87 [Pubmed: 30928696]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
MYP2 CDC11
Synthetic Lethality
Synthetic Lethality

A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition.

Low-BioGRID
247696

Curated By