BAIT
DNAJC17
1700025B16Rik, C87112, D9Bwg1371e
DnaJ (Hsp40) homolog, subfamily C, member 17
GO Process (2)
GO Function (0)
GO Component (2)
Gene Ontology Biological Process
Mus musculus
PREY
RPL35
L35, RP11-175D17.6
ribosomal protein L35
GO Process (13)
GO Function (3)
GO Component (5)
Gene Ontology Biological Process
- RNA metabolic process [TAS]
- SRP-dependent cotranslational protein targeting to membrane [TAS]
- cellular protein metabolic process [TAS]
- gene expression [TAS]
- mRNA metabolic process [TAS]
- nuclear-transcribed mRNA catabolic process, nonsense-mediated decay [TAS]
- translation [NAS, TAS]
- translational elongation [TAS]
- translational initiation [TAS]
- translational termination [TAS]
- viral life cycle [TAS]
- viral process [TAS]
- viral transcription [TAS]
Gene Ontology Molecular Function
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
DNAJC17 is localized in nuclear speckles and interacts with splicing machinery components.
DNAJC17 is a heat shock protein (HSP40) family member, identified in mouse as susceptibility gene for congenital hypothyroidism. DNAJC17 knockout mouse embryos die prior to implantation. In humans, germline homozygous mutations in DNAJC17 have been found in syndromic retinal dystrophy patients, while heterozygous mutations represent candidate pathogenic events for myeloproliferative disorders. Despite widespread expression and involvement in human diseases, DNAJC17 ... [more]
Sci Rep Dec. 17, 2017; 8(1);7794 [Pubmed: 29773831]
Throughput
- High Throughput
Curated By
- BioGRID