BAIT
CFL1
AA959946, Cof, n-cofilin
cofilin 1, non-muscle
GO Process (15)
GO Function (1)
GO Component (10)
Gene Ontology Biological Process
- actin filament organization [IMP]
- cell projection organization [ISO]
- cellular component movement [IMP]
- cytoskeleton organization [ISO]
- establishment of cell polarity [IMP]
- mitotic cytokinesis [IMP]
- negative regulation of cell size [ISO]
- neural crest cell migration [IMP]
- neural fold formation [IMP]
- positive regulation of actin filament depolymerization [IMP]
- protein import into nucleus [ISO]
- protein phosphorylation [IDA]
- regulation of cell morphogenesis [ISO]
- regulation of dendritic spine morphogenesis [ISO]
- response to amino acid [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
CAP1
RP23-121J14.1
CAP, adenylate cyclase-associated protein 1 (yeast)
GO Process (4)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.696 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID