BAIT
TUBA4A
M[a]4, Tuba4
tubulin, alpha 4A
GO Process (0)
GO Function (0)
GO Component (2)
Gene Ontology Cellular Component
Mus musculus
PREY
CLIC4
D0Jmb3, TU-74, mc3s5, mtCLIC, RP23-230K10.1
chloride intracellular channel 4 (mitochondrial)
GO Process (12)
GO Function (3)
GO Component (18)
Gene Ontology Biological Process
- angiogenesis [IMP]
- branching morphogenesis of an epithelial tube [IMP]
- cellular response to calcium ion [ISO]
- chloride transmembrane transport [ISO]
- chloride transport [ISO]
- endothelial cell morphogenesis [IMP]
- fertilization [IMP]
- keratinocyte differentiation [IMP, ISO]
- multicellular organism growth [IMP]
- negative regulation of cell migration [ISO]
- retina vasculature morphogenesis in camera-type eye [IMP]
- vacuolar acidification [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- apical part of cell [ISO]
- cell [IMP]
- cell surface [ISO]
- cell-cell junction [ISO]
- centrosome [ISO]
- cytoplasm [ISO]
- cytosol [ISO]
- extracellular vesicular exosome [ISO]
- integral component of membrane [ISS]
- intracellular [IMP, ISO]
- microtubule cytoskeleton [ISO]
- microvillus [ISO]
- midbody [ISO]
- mitochondrion [IDA, ISO]
- nuclear matrix [ISO]
- perinuclear region of cytoplasm [ISO]
- plasma membrane [ISO]
- vacuole [IMP]
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.728 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID