BAIT
RPA1
5031405K23Rik, 70kDa, AA589576, AW557552, RF-A, RP-A, Rpa, RP23-113D4.1
replication protein A1
GO Process (12)
GO Function (3)
GO Component (8)
Gene Ontology Biological Process
- DNA replication [ISO]
- base-excision repair [ISO]
- chromosome organization [IMP]
- double-strand break repair via homologous recombination [IMP, ISO]
- hemopoiesis [IMP]
- homeostasis of number of cells within a tissue [IMP]
- in utero embryonic development [IMP]
- meiotic nuclear division [IDA]
- mismatch repair [ISO]
- nucleotide-excision repair [ISO]
- positive regulation of cell proliferation [IMP]
- telomere maintenance [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
DDX1
AA409185, DBP-RB
DEAD (Asp-Glu-Ala-Asp) box polypeptide 1
GO Process (8)
GO Function (9)
GO Component (8)
Gene Ontology Biological Process
- ATP catabolic process [ISO]
- DNA duplex unwinding [ISO]
- double-strand break repair [ISO]
- nucleic acid phosphodiester bond hydrolysis [ISO]
- regulation of nucleic acid-templated transcription [ISO]
- response to exogenous dsRNA [IMP]
- response to virus [IMP]
- tRNA splicing, via endonucleolytic cleavage and ligation [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.734 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID