BAIT
AKAP5
3526401B18Rik, AKAP 150, AKAP-5, AKAP150, BB098886, Gm258, P150
A kinase (PRKA) anchor protein 5
GO Process (11)
GO Function (12)
GO Component (13)
Gene Ontology Biological Process
- cellular protein complex disassembly [ISO]
- negative regulation of adenylate cyclase activity [ISO]
- negative regulation of ion transport [ISO]
- negative regulation of potassium ion transport [ISO]
- positive regulation of NFAT protein import into nucleus [ISO]
- positive regulation of adenylate cyclase activity [ISO]
- positive regulation of cAMP biosynthetic process [ISO]
- positive regulation of calcium ion transport into cytosol [ISO]
- positive regulation of dendrite morphogenesis [ISO]
- positive regulation of protein kinase A signaling [ISO]
- positive regulation of protein phosphorylation [ISO]
Gene Ontology Molecular Function- G-protein coupled receptor binding [ISO]
- GABA receptor binding [ISO]
- actin binding [ISO]
- adenylate cyclase binding [ISO]
- cadherin binding [ISO]
- kinase binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- protein domain specific binding [ISO]
- protein kinase A regulatory subunit binding [ISO]
- protein kinase binding [ISO]
- protein phosphatase 2B binding [ISO]
- G-protein coupled receptor binding [ISO]
- GABA receptor binding [ISO]
- actin binding [ISO]
- adenylate cyclase binding [ISO]
- cadherin binding [ISO]
- kinase binding [ISO]
- protein binding [IPI]
- protein complex binding [ISO]
- protein domain specific binding [ISO]
- protein kinase A regulatory subunit binding [ISO]
- protein kinase binding [ISO]
- protein phosphatase 2B binding [ISO]
Gene Ontology Cellular Component
- asymmetric synapse [ISO]
- basolateral plasma membrane [ISO]
- cytoplasm [ISO]
- dendrite membrane [ISO]
- dendritic shaft [ISO]
- dendritic spine [ISO]
- dendritic spine membrane [ISO]
- filopodium membrane [ISO]
- neuronal cell body [ISO]
- perinuclear region of cytoplasm [ISO]
- plasma membrane [ISO]
- postsynaptic density [ISO]
- protein complex [ISO]
Mus musculus
PREY
EPB4.1L3
4.1B, DAL1P, Dal1, Epb41l3, NBL3
erythrocyte protein band 4.1-like 3
GO Process (9)
GO Function (1)
GO Component (7)
Gene Ontology Biological Process
- cortical cytoskeleton organization [TAS]
- cytoskeletal anchoring at plasma membrane [TAS]
- myelin maintenance [IMP]
- neuron projection morphogenesis [IMP]
- paranodal junction assembly [IMP]
- protein localization to juxtaparanode region of axon [IMP]
- protein localization to paranode region of axon [IMP]
- protein localization to plasma membrane [IMP]
- regulation of cell shape [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.768 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID