BAIT
MIF
GIF, Glif
macrophage migration inhibitory factor
GO Process (44)
GO Function (7)
GO Component (10)
Gene Ontology Biological Process
- DNA damage response, signal transduction by p53 class mediator [IMP]
- brain renin-angiotensin system [ISO]
- carboxylic acid metabolic process [ISO]
- cell aging [IMP]
- cell proliferation [ISO]
- cell surface receptor signaling pathway [ISO]
- drinking behavior [ISO]
- negative regulation of DNA damage response, signal transduction by p53 class mediator [IDA, ISO]
- negative regulation of apoptotic process [IDA, ISO]
- negative regulation of cell aging [ISO]
- negative regulation of cell cycle arrest [ISO]
- negative regulation of cellular protein metabolic process [IDA]
- negative regulation of gene expression [ISO]
- negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [ISO]
- negative regulation of mature B cell apoptotic process [IDA]
- negative regulation of myeloid cell apoptotic process [IMP]
- positive chemotaxis [ISO]
- positive regulation of B cell proliferation [ISO]
- positive regulation of ERK1 and ERK2 cascade [IDA, ISO]
- positive regulation of MAP kinase activity [IDA]
- positive regulation of acute inflammatory response [ISO]
- positive regulation of adaptive immune response [NAS]
- positive regulation of arachidonic acid secretion [IDA]
- positive regulation of axon regeneration [ISO]
- positive regulation of chemokine (C-X-C motif) ligand 2 production [IDA]
- positive regulation of cytokine secretion [ISO]
- positive regulation of fibroblast proliferation [IDA, ISO]
- positive regulation of glucose import [ISO]
- positive regulation of glycolytic process [ISO]
- positive regulation of immune response [ISO]
- positive regulation of lipopolysaccharide-mediated signaling pathway [IMP]
- positive regulation of myeloid leukocyte cytokine production involved in immune response [IMP]
- positive regulation of peptidyl-serine phosphorylation [IDA, ISO]
- positive regulation of peptidyl-tyrosine phosphorylation [IDA, ISO]
- positive regulation of phosphorylation [ISO]
- positive regulation of potassium ion transport [ISO]
- positive regulation of prostaglandin secretion involved in immune response [IMP]
- positive regulation of protein kinase A signaling [ISO]
- positive regulation of protein phosphorylation [IDA]
- positive regulation of smooth muscle cell migration [ISO]
- prostaglandin biosynthetic process [ISO]
- protein homotrimerization [ISO]
- regulation of cell proliferation [IMP]
- spermatogenesis [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
GORASP2
0610011A07Rik, 2410043M02Rik, 5730520M13Rik, 9430094F20Rik, AW552058, GOLPH2, GRASP55, GRS2, p59, RP23-428O15.1
golgi reassembly stacking protein 2
GO Process (0)
GO Function (0)
GO Component (1)
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.712 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID