BAIT
PLAT
AU020998, AW212668, D8Ertd2e, tPA
plasminogen activator, tissue
GO Process (8)
GO Function (1)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
KRT8
AA960620, AL022697, AU019895, Card2, EndoA, K8, Krt-2.8, Krt2-8
keratin 8
GO Process (9)
GO Function (3)
GO Component (12)
Gene Ontology Biological Process
- cell differentiation involved in embryonic placenta development [IGI]
- cell morphogenesis involved in differentiation [TAS]
- extrinsic apoptotic signaling pathway [IMP]
- hepatocyte apoptotic process [IMP]
- multicellular organismal development [TAS]
- response to hydrostatic pressure [ISO]
- response to other organism [IMP]
- sarcomere organization [ISO]
- tumor necrosis factor-mediated signaling pathway [IGI, IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Z disc [IDA, ISO]
- cell periphery [IDA]
- cell-cell junction [IDA]
- costamere [ISO]
- cytoplasm [ISO]
- dystrophin-associated glycoprotein complex [ISO]
- extracellular vesicular exosome [ISO]
- intermediate filament [IDA, ISO]
- intermediate filament cytoskeleton [ISO]
- keratin filament [ISO]
- nucleus [ISO]
- sarcolemma [IDA, ISO]
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.78 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID