BAIT
G6PDX
G28A, G6pd, Gpdx, RP23-436K3.17-003
glucose-6-phosphate dehydrogenase X-linked
GO Process (24)
GO Function (5)
GO Component (9)
Gene Ontology Biological Process
- NADP biosynthetic process [IDA, IMP]
- NADP metabolic process [ISO]
- NADPH regeneration [ISO]
- angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure [IMP]
- cellular response to oxidative stress [ISO]
- cholesterol biosynthetic process [ISO]
- cytokine production [IMP, ISO]
- erythrocyte development [IMP]
- erythrocyte maturation [ISO]
- glucose 6-phosphate metabolic process [ISO]
- glutathione metabolic process [IMP, ISO]
- interleukin-10 production [IMP]
- interleukin-12 production [IMP]
- negative regulation of protein glutathionylation [ISO]
- oxidation-reduction process [IMP, ISO]
- pentose biosynthetic process [IDA, IMP, ISO]
- pentose-phosphate shunt [ISO]
- pentose-phosphate shunt, oxidative branch [ISO]
- regulation of multicellular organism growth [IMP]
- regulation of neuron apoptotic process [ISO]
- response to ethanol [ISO]
- response to oxidative stress [IMP]
- ribose phosphate biosynthetic process [ISO]
- vasodilation by angiotensin involved in regulation of systemic arterial blood pressure [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
LONP1
1200017E13Rik, LON, Prss15
lon peptidase 1, mitochondrial
GO Process (10)
GO Function (13)
GO Component (5)
Gene Ontology Biological Process
- ATP catabolic process [IDA, ISO]
- cellular protein complex assembly [ISO]
- cellular response to oxidative stress [ISO]
- chaperone-mediated protein complex assembly [IBA]
- misfolded or incompletely synthesized protein catabolic process [IBA]
- mitochondrion organization [IBA, ISO]
- oxidation-dependent protein catabolic process [ISO]
- protein homooligomerization [ISO]
- proteolysis [IDA, ISO]
- proteolysis involved in cellular protein catabolic process [ISO]
Gene Ontology Molecular Function- ADP binding [ISO]
- ATP binding [ISO]
- ATP-dependent peptidase activity [IDA, ISO]
- ATPase activity [IDA]
- DNA polymerase binding [ISO]
- G-quadruplex DNA binding [ISO]
- mitochondrial heavy strand promoter anti-sense binding [IDA]
- mitochondrial heavy strand promoter sense binding [IDA]
- mitochondrial light strand promoter anti-sense binding [IDA, ISO]
- mitochondrial light strand promoter sense binding [IDA]
- sequence-specific DNA binding [ISO]
- single-stranded DNA binding [IDA]
- single-stranded RNA binding [ISO]
- ADP binding [ISO]
- ATP binding [ISO]
- ATP-dependent peptidase activity [IDA, ISO]
- ATPase activity [IDA]
- DNA polymerase binding [ISO]
- G-quadruplex DNA binding [ISO]
- mitochondrial heavy strand promoter anti-sense binding [IDA]
- mitochondrial heavy strand promoter sense binding [IDA]
- mitochondrial light strand promoter anti-sense binding [IDA, ISO]
- mitochondrial light strand promoter sense binding [IDA]
- sequence-specific DNA binding [ISO]
- single-stranded DNA binding [IDA]
- single-stranded RNA binding [ISO]
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.847 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID