BAIT
EHD4
2210022F10Rik, AI197390, AI846352, AV006278, Past2, RP23-348L16.8
EH-domain containing 4
GO Process (6)
GO Function (1)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
MTMR2
6030445P13Rik, RP23-133A3.2
myotubularin related protein 2
GO Process (14)
GO Function (4)
GO Component (11)
Gene Ontology Biological Process
- dendritic spine maintenance [ISO]
- dephosphorylation [IDA, IMP]
- inositol phosphate dephosphorylation [IDA]
- myelin assembly [IGI, IMP]
- negative regulation of endocytosis [ISO]
- negative regulation of excitatory postsynaptic membrane potential [ISO]
- negative regulation of myelination [IGI]
- negative regulation of receptor catabolic process [ISO]
- negative regulation of receptor internalization [ISO]
- neuron development [IGI]
- phosphatidylinositol dephosphorylation [IDA, ISO]
- phosphatidylinositol metabolic process [IMP]
- positive regulation of early endosome to late endosome transport [ISO]
- protein tetramerization [IPI]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.765 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID