BAIT
SOD2
MnSOD, Sod-2
superoxide dismutase 2, mitochondrial
GO Process (51)
GO Function (6)
GO Component (7)
Gene Ontology Biological Process
- age-dependent response to oxidative stress [IMP]
- age-dependent response to reactive oxygen species [ISO]
- apoptotic mitochondrial changes [IMP]
- detection of oxygen [IMP]
- erythrophore differentiation [IMP]
- glutathione metabolic process [IMP]
- heart development [IMP]
- hemopoiesis [IMP]
- hydrogen peroxide biosynthetic process [ISO]
- hydrogen peroxide metabolic process [ISO]
- intrinsic apoptotic signaling pathway in response to DNA damage [IMP]
- intrinsic apoptotic signaling pathway in response to oxidative stress [IMP]
- iron ion homeostasis [IMP]
- liver development [IMP]
- locomotory behavior [IMP]
- mitochondrion organization [IMP]
- negative regulation of apoptotic process [ISO]
- negative regulation of cell proliferation [ISO]
- negative regulation of fat cell differentiation [IMP]
- negative regulation of fibroblast proliferation [IDA]
- negative regulation of neuron apoptotic process [ISO]
- negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway [ISO]
- neuron development [IMP]
- oxidation-reduction process [ISO]
- oxygen homeostasis [ISO]
- positive regulation of nitric oxide biosynthetic process [IMP]
- post-embryonic development [IMP]
- protein homooligomerization [ISO]
- protein homotetramerization [ISO]
- regulation of blood pressure [IMP]
- regulation of catalytic activity [IMP]
- regulation of mitochondrial membrane potential [IMP]
- regulation of transcription from RNA polymerase II promoter [IDA, ISO]
- release of cytochrome c from mitochondria [IMP]
- removal of superoxide radicals [IDA, IMP, ISO]
- respiratory electron transport chain [IMP]
- response to activity [IMP]
- response to axon injury [IMP]
- response to drug [ISO]
- response to gamma radiation [IGI]
- response to hydrogen peroxide [IMP]
- response to hyperoxia [IMP]
- response to nutrient levels [ISO]
- response to oxidative stress [IGI, IMP]
- response to reactive oxygen species [IMP]
- response to superoxide [IMP, ISO]
- sensory perception of sound [IMP]
- superoxide anion generation [IMP]
- superoxide metabolic process [IMP, ISO]
- vasodilation [IMP]
- vasodilation by acetylcholine involved in regulation of systemic arterial blood pressure [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
NDUFB10
0610011B04Rik, 22kDa, PDSW
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 10
GO Process (0)
GO Function (0)
GO Component (4)
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.715 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID