BAIT
SLC17A7
2900052E22Rik, AI851913, Vglut1
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
GO Process (11)
GO Function (4)
GO Component (8)
Gene Ontology Biological Process
- L-glutamate import [IDA, IGI, IMP]
- long-term memory [IMP]
- phosphate ion transmembrane transport [ISO]
- phosphate ion transport [ISO]
- regulation of excitatory postsynaptic membrane potential [IMP]
- sequestering of neurotransmitter [IMP]
- sodium ion transmembrane transport [ISO]
- sodium-dependent phosphate transport [ISO]
- synaptic transmission [IMP]
- synaptic transmission, glutamatergic [IMP]
- synaptic vesicle lumen acidification [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
NLGN2
NL2, RP23-422L16.24
neuroligin 2
GO Process (23)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
- gephyrin clustering [IDA]
- jump response [ISO]
- locomotory exploration behavior [IMP]
- neuromuscular process controlling balance [IMP]
- neuron cell-cell adhesion [IBA, ISO]
- positive regulation of excitatory postsynaptic membrane potential [IMP]
- positive regulation of inhibitory postsynaptic membrane potential [IMP, ISO]
- positive regulation of synapse assembly [ISO]
- positive regulation of synaptic transmission, GABAergic [IMP]
- positive regulation of synaptic transmission, glutamatergic [IMP]
- postsynaptic density protein 95 clustering [IDA]
- postsynaptic membrane assembly [IDA]
- presynaptic membrane assembly [IDA, IMP, ISO]
- protein localization to synapse [IDA]
- regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity [IMP]
- regulation of respiratory gaseous exchange by neurological system process [IGI]
- regulation of synaptic transmission [IGI]
- sensory perception of pain [IMP]
- social behavior [ISO]
- synapse assembly [ISO]
- synapse organization [ISO]
- terminal button organization [ISO]
- thigmotaxis [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.708 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID