BAIT
POR
4933424M13Rik, CPR, CYPOR
P450 (cytochrome) oxidoreductase
GO Process (17)
GO Function (12)
GO Component (4)
Gene Ontology Biological Process
- cellular organofluorine metabolic process [ISO]
- demethylation [ISO]
- fatty acid oxidation [ISO]
- internal peptidyl-lysine acetylation [ISO]
- negative regulation of apoptotic process [ISO]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- negative regulation of lipase activity [ISO]
- nitrate catabolic process [ISO]
- nitric oxide catabolic process [ISO]
- oxidation-reduction process [IMP, ISO]
- positive regulation of cholesterol biosynthetic process [ISO]
- positive regulation of chondrocyte differentiation [ISO]
- positive regulation of monooxygenase activity [ISO]
- positive regulation of smoothened signaling pathway [ISO]
- positive regulation of steroid hormone biosynthetic process [ISO]
- regulation of cholesterol metabolic process [ISO]
- regulation of growth plate cartilage chondrocyte proliferation [ISO]
Gene Ontology Molecular Function- FMN binding [ISO]
- NADP binding [ISO]
- NADPH-hemoprotein reductase activity [IBA, ISO]
- cytochrome-b5 reductase activity, acting on NAD(P)H [ISO]
- electron carrier activity [ISO]
- enzyme binding [ISO]
- flavin adenine dinucleotide binding [ISO]
- hydrolase activity [ISO]
- iron-cytochrome-c reductase activity [ISO]
- nitric oxide dioxygenase activity [ISO]
- oxidoreductase activity [IMP]
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [IBA]
- FMN binding [ISO]
- NADP binding [ISO]
- NADPH-hemoprotein reductase activity [IBA, ISO]
- cytochrome-b5 reductase activity, acting on NAD(P)H [ISO]
- electron carrier activity [ISO]
- enzyme binding [ISO]
- flavin adenine dinucleotide binding [ISO]
- hydrolase activity [ISO]
- iron-cytochrome-c reductase activity [ISO]
- nitric oxide dioxygenase activity [ISO]
- oxidoreductase activity [IMP]
- oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen [IBA]
Gene Ontology Cellular Component
Mus musculus
PREY
PAK3
PAK-3, Pak65alpha, Pak65beta, Stk4, RP23-45O6.1
p21 protein (Cdc42/Rac)-activated kinase 3
GO Process (14)
GO Function (7)
GO Component (2)
Gene Ontology Biological Process
- MAPK cascade [ISO]
- actin cytoskeleton organization [IBA]
- activation of MAPK activity [ISO]
- axonogenesis [IMP]
- dendrite development [IMP]
- intracellular signal transduction [IBA]
- positive regulation of DNA biosynthetic process [ISO]
- positive regulation of dendritic spine morphogenesis [ISO]
- positive regulation of neuron apoptotic process [ISO]
- protein phosphorylation [IBA, ISO]
- regulation of actin filament polymerization [ISO]
- regulation of neuron projection development [ISO]
- response to stress [IBA]
- signal transduction by phosphorylation [IBA]
Gene Ontology Molecular Function
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.687 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID