BAIT
HMGB2
C80539, HMG-2, Hmg2
high mobility group box 2
GO Process (18)
GO Function (10)
GO Component (6)
Gene Ontology Biological Process
- base-excision repair, DNA ligation [ISO]
- cell chemotaxis [ISO]
- chromatin remodeling [IBA]
- male gonad development [IMP]
- negative regulation of extrinsic apoptotic signaling pathway via death domain receptors [IMP]
- negative regulation of transcription, DNA-templated [ISO]
- positive chemotaxis [ISO]
- positive regulation of DNA binding [IDA, ISO]
- positive regulation of endothelial cell proliferation [ISO]
- positive regulation of erythrocyte differentiation [ISO]
- positive regulation of megakaryocyte differentiation [ISO]
- positive regulation of nuclease activity [ISO]
- positive regulation of transcription from RNA polymerase II promoter [IMP, ISO]
- positive regulation of transcription, DNA-templated [ISO]
- regulation of transcription from RNA polymerase II promoter [IDA, ISO]
- response to steroid hormone [IMP]
- spermatid nucleus differentiation [IMP]
- spermatogenesis [IMP]
Gene Ontology Molecular Function- DNA binding [ISO]
- DNA binding, bending [ISO]
- RAGE receptor binding [ISO]
- chemoattractant activity [ISO]
- chromatin binding [IBA]
- damaged DNA binding [ISO]
- poly(A) RNA binding [ISO]
- protein domain specific binding [IPI]
- sequence-specific DNA binding transcription factor activity [ISO]
- transcription regulatory region DNA binding [ISO]
- DNA binding [ISO]
- DNA binding, bending [ISO]
- RAGE receptor binding [ISO]
- chemoattractant activity [ISO]
- chromatin binding [IBA]
- damaged DNA binding [ISO]
- poly(A) RNA binding [ISO]
- protein domain specific binding [IPI]
- sequence-specific DNA binding transcription factor activity [ISO]
- transcription regulatory region DNA binding [ISO]
Gene Ontology Cellular Component
Mus musculus
PREY
PGD
0610042A05Rik, AU019875, C78335, RP23-249G3.4
phosphogluconate dehydrogenase
GO Process (3)
GO Function (1)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.772 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID