BAIT
STRN
AU022939, D130055P19
striatin, calmodulin binding protein
GO Process (4)
GO Function (6)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
PPP2CB
AI115466, D8Ertd766e, PP2Ac
protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform
GO Process (8)
GO Function (4)
GO Component (4)
Gene Ontology Biological Process
- apoptotic mitochondrial changes [IMP]
- negative regulation of Ras protein signal transduction [ISO]
- proteasome-mediated ubiquitin-dependent protein catabolic process [IMP]
- protein dephosphorylation [ISO]
- regulation of gene expression [IMP]
- response to antibiotic [IMP]
- response to endoplasmic reticulum stress [IMP]
- response to hydrogen peroxide [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.84 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID