BUR2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
SET2
Gene Ontology Biological Process
- DNA-templated transcription, elongation [IDA, IPI]
- DNA-templated transcription, termination [IMP]
- ascospore formation [IMP]
- histone deacetylation [IMP]
- histone methylation [IDA, IMP]
- negative regulation of antisense RNA transcription [IMP]
- negative regulation of histone H3-K14 acetylation [IMP]
- negative regulation of histone H3-K9 acetylation [IMP]
- negative regulation of reciprocal meiotic recombination [IMP]
- positive regulation of histone acetylation [IGI]
- regulation of DNA-dependent DNA replication initiation [IMP]
- regulation of histone exchange [IMP]
- regulation of transcription, DNA-templated [IDA, IMP]
Gene Ontology Molecular Function
Phenotypic Enhancement
A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.
Publication
Regulation of histone modification and cryptic transcription by the Bur1 and Paf1 complexes.
The Bur1-Bur2 and Paf1 complexes function during transcription elongation and affect histone modifications. Here we describe new roles for Bur1-Bur2 and the Paf1 complex. We find that histone H3 K36 tri-methylation requires specific components of the Paf1 complex and that K36 tri-methylation is more strongly affected at the 5' ends of genes in paf1delta and bur2delta strains in parallel with ... [more]
Throughput
- Low Throughput
Ontology Terms
- phenotype: protein/peptide modification (APO:0000131)
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
BUR2 SET2 | Synthetic Lethality Synthetic Lethality A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition. | Low | - | BioGRID | 608882 | |
BUR2 SET2 | Synthetic Rescue Synthetic Rescue A genetic interaction is inferred when mutations or deletions of one gene rescues the lethality or growth defect of a strain mutated or deleted for another gene. | Low | - | BioGRID | 608881 | |
BUR2 SET2 | Synthetic Rescue Synthetic Rescue A genetic interaction is inferred when mutations or deletions of one gene rescues the lethality or growth defect of a strain mutated or deleted for another gene. | Low | - | BioGRID | 574051 |
Curated By
- BioGRID