BAIT
RAB1
Gtbp, Rab-1, Rab1A, Ypt1, mKIAA3012, RP23-19L22.4
RAB1, member RAS oncogene family
GO Process (18)
GO Function (4)
GO Component (10)
Gene Ontology Biological Process
- ER to Golgi vesicle-mediated transport [IBA, ISA, ISO]
- GTP catabolic process [IBA, ISO]
- Golgi organization [ISO]
- Rab protein signal transduction [IBA]
- autophagic vacuole assembly [IBA, ISO]
- autophagy [ISO]
- cargo loading into COPII-coated vesicle [ISO]
- cell migration [IMP, ISO]
- defense response to bacterium [ISO]
- endocytosis [ISO]
- growth hormone secretion [ISO]
- interleukin-8 secretion [ISO]
- intracellular protein transport [TAS]
- melanosome transport [IMP]
- positive regulation of glycoprotein metabolic process [ISO]
- substrate adhesion-dependent cell spreading [IMP]
- vesicle transport along microtubule [ISO]
- virion assembly [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
RTN4
1110020G17Rik, AA407876, AA409940, AA960376, ASY, C130026I10Rik, NOGO, NSP-CL, NgA, Nogo-A, Nogo-B, Nogo-C, mKIAA0886, mKIAA4153, RP23-176O5.4
reticulon 4
GO Process (19)
GO Function (3)
GO Component (13)
Gene Ontology Biological Process
- angiogenesis [IMP]
- axonal fasciculation [IMP, ISO]
- cardiac epithelial to mesenchymal transition [IMP]
- cerebral cortex radial glia guided migration [IMP]
- endoplasmic reticulum tubular network organization [ISO]
- negative regulation of axon extension [IMP, ISO, ISS]
- negative regulation of axonogenesis [ISO]
- negative regulation of cell growth [ISO]
- negative regulation of neuron differentiation [ISO]
- negative regulation of neuron projection development [ISO]
- negative regulation of neuron projection regeneration [ISO]
- nervous system development [IDA]
- positive regulation of dopamine secretion [ISO]
- positive regulation of glial cell differentiation [ISO]
- regulation of axon regeneration [ISO]
- regulation of branching morphogenesis of a nerve [IMP, ISO]
- regulation of cell migration [ISO]
- regulation of nervous system development [IMP]
- regulation of sensory perception of pain [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- cell projection [IDA]
- cytoplasm [ISO]
- endoplasmic reticulum [IDA, ISO]
- extracellular vesicular exosome [ISO]
- integral component of endoplasmic reticulum membrane [ISO, ISS]
- intracellular [ISO]
- myelin sheath [ISO]
- neuron projection [ISO]
- neuronal cell body [IDA, ISO]
- neuronal postsynaptic density [IDA]
- nuclear envelope [ISO, ISS]
- plasma membrane [ISO]
- protein complex [ISO]
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.745 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID