BAIT
GAD2
6330404F12Rik, GAD(65), GAD65, Gad-2, RP23-407K8.5
glutamic acid decarboxylase 2
GO Process (1)
GO Function (4)
GO Component (9)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
SLC17A7
2900052E22Rik, AI851913, Vglut1
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
GO Process (11)
GO Function (4)
GO Component (8)
Gene Ontology Biological Process
- L-glutamate import [IDA, IGI, IMP]
- long-term memory [IMP]
- phosphate ion transmembrane transport [ISO]
- phosphate ion transport [ISO]
- regulation of excitatory postsynaptic membrane potential [IMP]
- sequestering of neurotransmitter [IMP]
- sodium ion transmembrane transport [ISO]
- sodium-dependent phosphate transport [ISO]
- synaptic transmission [IMP]
- synaptic transmission, glutamatergic [IMP]
- synaptic vesicle lumen acidification [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.713 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID