BAIT
TAOK3
2900006A08Rik, A130052D22, A430105I05Rik
TAO kinase 3
GO Process (12)
GO Function (3)
GO Component (2)
Gene Ontology Biological Process
- MAPK cascade [IBA, ISO]
- activation of MAPKK activity [IBA]
- cellular response to DNA damage stimulus [ISO]
- intracellular signal transduction [IBA]
- mitotic G2 DNA damage checkpoint [ISO]
- negative regulation of JNK cascade [ISO]
- positive regulation of JNK cascade [ISO]
- positive regulation of JUN kinase activity [ISO]
- positive regulation of stress-activated MAPK cascade [ISO]
- protein autophosphorylation [ISO]
- protein phosphorylation [IBA, ISO]
- response to stress [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
SNX2
0610030A03Rik
sorting nexin 2
GO Process (6)
GO Function (5)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.704 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID