BAIT
PURB
2310015K15Rik, AA114818, Cager-2, D11Bwg0414e, RP23-74L9.2
purine rich element binding protein B
GO Process (7)
GO Function (13)
GO Component (3)
Gene Ontology Biological Process
- apoptotic process [NAS]
- cell differentiation [NAS]
- cell proliferation [NAS]
- negative regulation of transcription from RNA polymerase II promoter [IDA, IGI]
- negative regulation of transcription, DNA-templated [IDA, ISO]
- negative regulation of translation [ISO]
- transcription from RNA polymerase II promoter [IDA]
Gene Ontology Molecular Function- RNA binding [IDA]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- SMAD binding [IDA]
- double-stranded DNA binding [IDA]
- mRNA binding [IDA]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- purine-rich negative regulatory element binding [ISO]
- sequence-specific DNA binding transcription factor activity [IDA]
- single-stranded DNA binding [IDA, ISO]
- transcription factor binding [IPI]
- translation repressor activity, nucleic acid binding [ISO]
- RNA binding [IDA]
- RNA polymerase II regulatory region sequence-specific DNA binding [IDA]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [IDA]
- SMAD binding [IDA]
- double-stranded DNA binding [IDA]
- mRNA binding [IDA]
- poly(A) RNA binding [ISO]
- protein binding [IPI]
- purine-rich negative regulatory element binding [ISO]
- sequence-specific DNA binding transcription factor activity [IDA]
- single-stranded DNA binding [IDA, ISO]
- transcription factor binding [IPI]
- translation repressor activity, nucleic acid binding [ISO]
Gene Ontology Cellular Component
Mus musculus
PREY
VPS33A
3830421M04Rik, AI503300, AW048546, AW554476, bf
vacuolar protein sorting 33A (yeast)
GO Process (6)
GO Function (1)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.802 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID