BAIT
PSMC3
TBP-1, RP23-263H8.1
proteasome (prosome, macropain) 26S subunit, ATPase 3
GO Process (1)
GO Function (0)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Mus musculus
PREY
ZPR1
AI303781, Zfp259, Znf259
ZPR1 zinc finger
GO Process (17)
GO Function (4)
GO Component (11)
Gene Ontology Biological Process
- Cajal body organization [IMP, ISO]
- DNA endoreduplication [IMP]
- apoptotic process involved in development [IMP]
- axon development [IMP, ISO]
- cellular response to epidermal growth factor stimulus [ISO]
- inner cell mass cell proliferation [IMP]
- microtubule cytoskeleton organization [IMP]
- negative regulation of motor neuron apoptotic process [IMP]
- positive regulation of RNA splicing [ISO]
- positive regulation of gene expression [IMP, ISO]
- positive regulation of growth [IMP]
- positive regulation of protein import into nucleus [IMP, ISO]
- positive regulation of transcription involved in G1/S transition of mitotic cell cycle [ISO]
- pre-mRNA catabolic process [ISO]
- regulation of myelination [IMP]
- spinal cord development [IMP]
- trophectodermal cell proliferation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.765 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID