BAIT
GIGYF2
2610016F01Rik, A830080H02Rik, AI852361, AW259676, BC006835, Tnrc15, mKIAA0642
GRB10 interacting GYF protein 2
GO Process (12)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
- adult locomotory behavior [IMP]
- cellular protein metabolic process [IMP]
- feeding behavior [IMP]
- homeostasis of number of cells within a tissue [IMP]
- insulin-like growth factor receptor signaling pathway [IMP]
- mitotic G1 DNA damage checkpoint [IMP]
- multicellular organism growth [IMP]
- musculoskeletal movement [IMP]
- negative regulation of translation [ISO]
- neuromuscular process controlling balance [IMP]
- post-embryonic development [IMP]
- spinal cord motor neuron differentiation [IMP]
Gene Ontology Molecular Function
Mus musculus
PREY
AGO2
1110029L17Rik, 2310051F07Rik, AI225898, AL022874, AW546247, ENSMUSG00000072493, Eif2c2, Gerp95, Gm10365, mKIAA4215
argonaute RISC catalytic subunit 2
GO Process (12)
GO Function (9)
GO Component (11)
Gene Ontology Biological Process
- RNA phosphodiester bond hydrolysis, endonucleolytic [IDA, ISO]
- gene silencing by RNA [IMP]
- mRNA cleavage [IMP]
- mRNA cleavage involved in gene silencing by miRNA [ISO]
- miRNA metabolic process [IDA]
- negative regulation of translation involved in gene silencing by miRNA [ISO]
- negative regulation of translational initiation [ISO]
- positive regulation of gene expression [IMP]
- positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay [IMP]
- positive regulation of nuclear-transcribed mRNA poly(A) tail shortening [IMP]
- post-embryonic development [IMP]
- pre-miRNA processing [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.8335 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID