BAIT
ISG15
G1p2, IGI15, IP17, Irfp, UCRP
ISG15 ubiquitin-like modifier
GO Process (9)
GO Function (2)
GO Component (1)
Gene Ontology Biological Process
- ISG15-protein conjugation [IDA, ISO]
- defense response to bacterium [IMP, ISO]
- defense response to virus [IMP, ISO]
- modification-dependent protein catabolic process [IDA]
- negative regulation of protein ubiquitination [ISO]
- negative regulation of viral genome replication [ISO]
- positive regulation of erythrocyte differentiation [IMP]
- regulation of interferon-gamma production [ISO]
- response to type I interferon [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
ATIC
2610509C24Rik, AA536954, AW212393
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
GO Process (5)
GO Function (3)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.8045 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID