BAIT
ZFAND2B
1110060O18Rik, C81256
zinc finger, AN1 type domain 2B
GO Process (0)
GO Function (0)
GO Component (0)
Mus musculus
PREY
BAG6
2410045D21Rik, AA408914, BAG-6, Bat3, D17H6S52E, G3, Scythe
BCL2-associated athanogene 6
GO Process (17)
GO Function (6)
GO Component (7)
Gene Ontology Biological Process
- antigen processing and presentation of peptide antigen via MHC class I [TAS]
- brain development [IMP]
- embryo development [IMP]
- internal peptidyl-lysine acetylation [ISO]
- intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator [ISO]
- intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress [IMP]
- kidney development [IMP]
- lung development [IMP]
- negative regulation of apoptotic process [IGI]
- negative regulation of proteasomal ubiquitin-dependent protein catabolic process [IMP]
- negative regulation of proteolysis [IMP]
- protein stabilization [IMP]
- regulation of apoptotic process [IMP]
- spermatogenesis [IMP]
- synaptonemal complex assembly [IMP]
- tail-anchored membrane protein insertion into ER membrane [ISO]
- ubiquitin-dependent protein catabolic process [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.7885 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID