BAIT
EVL
AI528774
Ena-vasodilator stimulated phosphoprotein
GO Process (10)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- actin filament-based movement [NAS]
- actin nucleation [NAS]
- actin polymerization or depolymerization [IDA]
- axon guidance [NAS]
- barbed-end actin filament capping [NAS]
- negative regulation of epithelial cell migration [ISO]
- negative regulation of ruffle assembly [ISO]
- platelet activation [NAS]
- positive regulation of actin filament polymerization [IDA]
- positive regulation of stress fiber assembly [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
BAIAP2
IRSp53, R75030, RP23-390H16.1
brain-specific angiogenesis inhibitor 1-associated protein 2
GO Process (9)
GO Function (4)
GO Component (13)
Gene Ontology Biological Process
- Rho protein signal transduction [TAS]
- actin crosslink formation [IMP]
- actin filament bundle assembly [IGI, IMP]
- dendrite development [IMP]
- positive regulation of dendritic spine morphogenesis [ISO]
- regulation of actin cytoskeleton organization [ISO]
- regulation of cell shape [IMP]
- regulation of synaptic plasticity [IMP]
- response to bacterium [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.794 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID