BAIT
SLC4A4
AI835705, NBC, NBC1
solute carrier family 4 (anion exchanger), member 4
GO Process (7)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
CAR2
AI131712, CAII, Ca2, Car-2, Ltw-5, Lvtw-5
carbonic anhydrase 2
GO Process (13)
GO Function (2)
GO Component (11)
Gene Ontology Biological Process
- angiotensin-activated signaling pathway [ISO]
- carbon dioxide transport [IC, IMP]
- morphogenesis of an epithelium [IMP]
- positive regulation of bone resorption [ISO]
- positive regulation of cellular pH reduction [IMP, ISO]
- positive regulation of dipeptide transmembrane transport [IMP]
- positive regulation of osteoclast differentiation [ISO]
- positive regulation of synaptic transmission, GABAergic [IGI]
- regulation of anion transport [ISO]
- regulation of chloride transport [IMP]
- regulation of intracellular pH [IMP]
- regulation of pH [IC]
- secretion [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.8035 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID