BAIT
CACYBP
SIP
calcyclin binding protein
GO Process (4)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
CARM1
Prmt4
coactivator-associated arginine methyltransferase 1
GO Process (18)
GO Function (11)
GO Component (4)
Gene Ontology Biological Process
- endochondral bone morphogenesis [IMP]
- histone H3-R17 methylation [IDA]
- histone H3-R2 methylation [ISO]
- histone arginine methylation [IDA]
- histone methylation [IDA, ISO]
- intracellular estrogen receptor signaling pathway [IGI]
- intracellular steroid hormone receptor signaling pathway [IDA]
- negative regulation of dendrite development [ISO]
- negative regulation of protein binding [IDA]
- peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [IDA]
- positive regulation of cell proliferation [IMP, ISO]
- positive regulation of fat cell differentiation [IMP]
- protein methylation [IMP]
- regulation of growth plate cartilage chondrocyte proliferation [IMP]
- regulation of intracellular estrogen receptor signaling pathway [IDA]
- regulation of mRNA binding [ISO]
- regulation of transcription, DNA-templated [IDA]
- response to cAMP [ISO]
Gene Ontology Molecular Function- histone methyltransferase activity [IDA, ISO]
- histone methyltransferase activity (H3-R17 specific) [IDA]
- ligand-dependent nuclear receptor transcription coactivator activity [IDA]
- lysine-acetylated histone binding [IDA]
- protein binding [IPI]
- protein homodimerization activity [IPI]
- protein methyltransferase activity [IDA]
- protein-arginine N-methyltransferase activity [IDA]
- protein-arginine omega-N asymmetric methyltransferase activity [IDA]
- transcription coactivator activity [IDA]
- transcription regulatory region DNA binding [IMP]
- histone methyltransferase activity [IDA, ISO]
- histone methyltransferase activity (H3-R17 specific) [IDA]
- ligand-dependent nuclear receptor transcription coactivator activity [IDA]
- lysine-acetylated histone binding [IDA]
- protein binding [IPI]
- protein homodimerization activity [IPI]
- protein methyltransferase activity [IDA]
- protein-arginine N-methyltransferase activity [IDA]
- protein-arginine omega-N asymmetric methyltransferase activity [IDA]
- transcription coactivator activity [IDA]
- transcription regulatory region DNA binding [IMP]
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.7475 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID