BAIT
GOPC
2210402P09Rik, AI844555, CAL, FIG, GOPC1, PIST
golgi associated PDZ and coiled-coil motif containing
GO Process (4)
GO Function (6)
GO Component (7)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
CBS
AI047524, AI303044, HIP4
cystathionine beta-synthase
GO Process (17)
GO Function (8)
GO Component (5)
Gene Ontology Biological Process
- blood vessel remodeling [IMP]
- cartilage development involved in endochondral bone morphogenesis [IMP]
- cellular response to hypoxia [ISO]
- cerebellum morphogenesis [IMP]
- cysteine biosynthetic process [IMP]
- cysteine biosynthetic process via cystathionine [IBA]
- endochondral ossification [IMP]
- homocysteine metabolic process [IMP, ISO]
- hydrogen sulfide biosynthetic process [IBA, ISO]
- maternal process involved in female pregnancy [IMP]
- negative regulation of apoptotic process [ISO]
- regulation of JUN kinase activity [IMP]
- regulation of blood vessel size [IMP]
- regulation of cGMP metabolic process [IMP]
- response to folic acid [IMP]
- superoxide metabolic process [IMP]
- transsulfuration [ISO]
Gene Ontology Molecular Function
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.92 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID