BAIT
AKT2
2410016A19Rik, AW554154, PKB, PKBbeta
thymoma viral proto-oncogene 2
GO Process (30)
GO Function (5)
GO Component (8)
Gene Ontology Biological Process
- activation of Ral GTPase activity [IGI]
- cellular response to insulin stimulus [IDA, ISO]
- cellular response to organic cyclic compound [ISO]
- insulin receptor signaling pathway [IDA, ISO]
- intracellular protein transmembrane transport [IMP]
- negative regulation of RNA splicing [ISO]
- negative regulation of apoptotic process [ISO]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- negative regulation of plasma membrane long-chain fatty acid transport [ISO]
- peripheral nervous system myelin maintenance [IMP]
- positive regulation of cell migration [ISO]
- positive regulation of cell motility [ISO]
- positive regulation of fatty acid beta-oxidation [ISO]
- positive regulation of gene expression [ISO]
- positive regulation of glucose import [ISO]
- positive regulation of glucose import in response to insulin stimulus [IGI]
- positive regulation of glucose metabolic process [ISO]
- positive regulation of glycogen biosynthetic process [ISO]
- positive regulation of nitric oxide biosynthetic process [ISO]
- positive regulation of peptidyl-serine phosphorylation [ISO]
- positive regulation of positive chemotaxis [ISO]
- positive regulation of protein phosphorylation [IDA, ISO]
- positive regulation of protein targeting to membrane [IMP]
- positive regulation of signal transduction [ISO]
- positive regulation of sodium ion transport [ISO]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of vesicle fusion [IMP]
- protein kinase B signaling [ISO]
- protein localization to plasma membrane [IGI]
- protein phosphorylation [IDA, ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
CDC37
p50, p50Cdc37
cell division cycle 37
GO Process (4)
GO Function (8)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.745 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID