BAIT
ARPC2
2210023N03Rik, 34kDa, p34-Arc
actin related protein 2/3 complex, subunit 2
GO Process (4)
GO Function (3)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
CORO1B
coronin, actin binding protein 1B
GO Process (10)
GO Function (4)
GO Component (9)
Gene Ontology Biological Process
- actin cytoskeleton organization [IBA]
- actin filament branching [ISO]
- actin filament bundle assembly [ISO]
- cell migration [ISO]
- endothelial cell chemotaxis [ISO]
- negative regulation of Arp2/3 complex-mediated actin nucleation [ISO]
- positive regulation of lamellipodium morphogenesis [ISO]
- protein localization to cell leading edge [ISO]
- ruffle organization [ISO]
- wound healing [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.8005 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID