BAIT
FHL1
FHL-1, KyoT, RAM14-1, SLIM, SLIM-1, RP23-71G11.1
four and a half LIM domains 1
GO Process (6)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
- negative regulation of G1/S transition of mitotic cell cycle [ISO]
- negative regulation of G2/M transition of mitotic cell cycle [ISO]
- negative regulation of cell growth [ISO]
- positive regulation of potassium ion transport [ISO]
- regulation of membrane depolarization [ISO]
- regulation of potassium ion transmembrane transporter activity [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
CSNK1D
1200006A05Rik, AA409348, D930010H05Rik, RP23-378G22.2
casein kinase 1, delta
GO Process (11)
GO Function (7)
GO Component (8)
Gene Ontology Biological Process
- Wnt signaling pathway [IBA]
- circadian regulation of gene expression [IMP]
- endocytosis [IBA]
- peptidyl-serine phosphorylation [IBA]
- positive regulation of canonical Wnt signaling pathway [ISO]
- positive regulation of proteasomal ubiquitin-dependent protein catabolic process [IMP]
- positive regulation of protein phosphorylation [ISO]
- protein phosphorylation [IDA, IMP, ISO]
- regulation of cell shape [IBA]
- regulation of circadian rhythm [IMP]
- spindle assembly [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.747 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID