BAIT
CSNK2B
casein kinase 2, beta polypeptide
GO Process (5)
GO Function (5)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
CSNK2A1
Csnk2a1-rs4, RP23-452D3.3
casein kinase 2, alpha 1 polypeptide
GO Process (9)
GO Function (6)
GO Component (5)
Gene Ontology Biological Process
- mitotic spindle checkpoint [ISO]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- positive regulation of Wnt signaling pathway [ISO]
- positive regulation of cell growth [ISO]
- positive regulation of cell proliferation [ISO]
- positive regulation of protein catabolic process [ISO]
- protein autophosphorylation [IDA]
- protein phosphorylation [IDA, ISO]
- regulation of catalytic activity [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.8325 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID