BAIT
RPLP0
36B4, Arbp, L10E
ribosomal protein, large, P0
GO Process (1)
GO Function (1)
GO Component (9)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
DNAJA1
Hsj2, Nedd7, RP23-135L5.1
DnaJ (Hsp40) homolog, subfamily A, member 1
GO Process (12)
GO Function (6)
GO Component (4)
Gene Ontology Biological Process
- DNA damage response, detection of DNA damage [ISO]
- androgen receptor signaling pathway [IMP]
- negative regulation of JUN kinase activity [ISO]
- negative regulation of apoptotic process [ISO]
- negative regulation of protein ubiquitination [ISO]
- positive regulation of apoptotic process [ISO]
- protein localization to mitochondrion [ISO]
- protein refolding [IBA]
- regulation of protein transport [ISO]
- sperm motility [IMP]
- spermatogenesis [IMP]
- toxin transport [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.8005 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID