BAIT
TCP1
AI528772, CCT, Cct1, Ccta, TRic, Tcp-1, Tp63, c-cpn, p63, RP23-351C7.3
t-complex protein 1
GO Process (4)
GO Function (3)
GO Component (13)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi apparatus [IDA]
- acrosomal vesicle [IDA]
- cell body [IDA]
- centrosome [ISO]
- chaperonin-containing T-complex [IDA]
- extracellular vesicular exosome [ISO]
- heterochromatin [ISO]
- microtubule [ISO]
- microtubule organizing center [IDA]
- myelin sheath [IDA]
- nuclear heterochromatin [IDA]
- pericentriolar material [IDA]
- zona pellucida receptor complex [IDA]
Mus musculus
PREY
GBA
GBA1, GC, GCase, GLUC, betaGC
glucosidase, beta, acid
GO Process (15)
GO Function (2)
GO Component (3)
Gene Ontology Biological Process
- cellular response to tumor necrosis factor [ISO]
- ceramide biosynthetic process [ISO]
- glucosylceramide catabolic process [ISO]
- negative regulation of MAP kinase activity [ISO]
- negative regulation of interleukin-6 production [ISO]
- positive regulation of protein dephosphorylation [ISO]
- regulation of water loss via skin [ISO]
- response to estrogen [ISO]
- response to glucocorticoid [ISO]
- response to pH [ISO]
- response to testosterone [ISO]
- response to thyroid hormone [ISO]
- skin morphogenesis [ISO]
- sphingosine biosynthetic process [ISO]
- termination of signal transduction [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.826 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID