GNG2
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
ADRBK1
Gene Ontology Biological Process
- G-protein coupled receptor signaling pathway [IDA, ISO]
- cardiac muscle contraction [ISO]
- desensitization of G-protein coupled receptor protein signaling pathway [IGI, IMP, ISO]
- follicle-stimulating hormone signaling pathway [ISO]
- heart development [IMP]
- negative regulation of G-protein coupled receptor protein signaling pathway [ISO]
- negative regulation of striated muscle contraction [ISO]
- negative regulation of the force of heart contraction by chemical signal [ISO]
- peptidyl-serine phosphorylation [IDA]
- peptidyl-threonine phosphorylation [IDA]
- positive regulation of catecholamine secretion [ISO]
- protein phosphorylation [IDA, IMP, ISO]
- receptor internalization [ISO]
- regulation of the force of heart contraction [IGI]
- response to organic cyclic compound [ISO]
- response to oxidative stress [ISO]
- tachykinin receptor signaling pathway [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Quantitative Score
- 0.8925 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
ADRBK1 GNG2 | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - |
Curated By
- BioGRID