BAIT
FHIT
AW045638, Fra14A2
fragile histidine triad gene
GO Process (6)
GO Function (6)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Mus musculus
PREY
GSN
ADF, RP23-186B18.2
gelsolin
GO Process (9)
GO Function (2)
GO Component (11)
Gene Ontology Biological Process
- actin filament polymerization [ISO]
- actin filament severing [ISO]
- actin polymerization or depolymerization [ISO]
- apoptotic process [ISO]
- cellular response to cadmium ion [ISO]
- cilium morphogenesis [ISO]
- phosphatidylinositol-mediated signaling [ISO]
- regulation of cell adhesion [ISO]
- vesicle-mediated transport [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.753 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID