BAIT
CCT3
AL024092, Cctg, Tcp1-rs3, TriC-P5
chaperonin containing Tcp1, subunit 3 (gamma)
GO Process (3)
GO Function (2)
GO Component (8)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
IGBP1
AI115586, AI662457, AW208785, C81413, Pc52, Tap42, p52
immunoglobulin (CD79A) binding protein 1
GO Process (10)
GO Function (6)
GO Component (2)
Gene Ontology Biological Process
- negative regulation of apoptotic signaling pathway [IMP]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- negative regulation of protein dephosphorylation [IDA]
- negative regulation of stress-activated MAPK cascade [ISO]
- negative regulation of transcription from RNA polymerase II promoter [ISO]
- positive regulation of dephosphorylation [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
- regulation of microtubule-based movement [ISO]
- response to interleukin-1 [ISO]
- response to tumor necrosis factor [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.811 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID