BAIT
AIP
AA408703, AW476050, Ara9, D19Bwg1412e, Fkbp16, Xap2
aryl-hydrocarbon receptor-interacting protein
GO Process (6)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
LAMP1
AI196048, CD107a, Lamp-1
lysosomal-associated membrane protein 1
GO Process (9)
GO Function (3)
GO Component (21)
Gene Ontology Biological Process
- Golgi to lysosome transport [ISO]
- autophagic cell death [ISO]
- establishment of protein localization to organelle [ISO]
- granzyme-mediated apoptotic signaling pathway [ISO]
- positive regulation of natural killer cell degranulation [ISO]
- positive regulation of natural killer cell mediated cytotoxicity [ISO]
- protein stabilization [IMP]
- regulation of organelle transport along microtubule [ISO]
- spermatogenesis [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- alveolar lamellar body [ISO]
- cell surface [IDA]
- cytolytic granule [IDA]
- cytoplasm [ISO]
- cytoplasmic vesicle [ISO]
- dendrite [ISO]
- endosome [IDA]
- external side of plasma membrane [IDA]
- extracellular vesicular exosome [ISO]
- late endosome [IDA, ISO]
- lysosome [IDA, ISO]
- melanosome [IDA]
- membrane [ISO]
- multivesicular body [IDA, ISO]
- neuronal cell body [ISO]
- phagolysosome membrane [IDA]
- plasma membrane [ISO]
- sarcolemma [IDA]
- synaptic vesicle [IDA]
- vacuole [ISO]
- vesicle [IDA]
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.747 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID