BAIT
CDC37
p50, p50Cdc37
cell division cycle 37
GO Process (4)
GO Function (8)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
LONP1
1200017E13Rik, LON, Prss15
lon peptidase 1, mitochondrial
GO Process (10)
GO Function (13)
GO Component (5)
Gene Ontology Biological Process
- ATP catabolic process [IDA, ISO]
- cellular protein complex assembly [ISO]
- cellular response to oxidative stress [ISO]
- chaperone-mediated protein complex assembly [IBA]
- misfolded or incompletely synthesized protein catabolic process [IBA]
- mitochondrion organization [IBA, ISO]
- oxidation-dependent protein catabolic process [ISO]
- protein homooligomerization [ISO]
- proteolysis [IDA, ISO]
- proteolysis involved in cellular protein catabolic process [ISO]
Gene Ontology Molecular Function- ADP binding [ISO]
- ATP binding [ISO]
- ATP-dependent peptidase activity [IDA, ISO]
- ATPase activity [IDA]
- DNA polymerase binding [ISO]
- G-quadruplex DNA binding [ISO]
- mitochondrial heavy strand promoter anti-sense binding [IDA]
- mitochondrial heavy strand promoter sense binding [IDA]
- mitochondrial light strand promoter anti-sense binding [IDA, ISO]
- mitochondrial light strand promoter sense binding [IDA]
- sequence-specific DNA binding [ISO]
- single-stranded DNA binding [IDA]
- single-stranded RNA binding [ISO]
- ADP binding [ISO]
- ATP binding [ISO]
- ATP-dependent peptidase activity [IDA, ISO]
- ATPase activity [IDA]
- DNA polymerase binding [ISO]
- G-quadruplex DNA binding [ISO]
- mitochondrial heavy strand promoter anti-sense binding [IDA]
- mitochondrial heavy strand promoter sense binding [IDA]
- mitochondrial light strand promoter anti-sense binding [IDA, ISO]
- mitochondrial light strand promoter sense binding [IDA]
- sequence-specific DNA binding [ISO]
- single-stranded DNA binding [IDA]
- single-stranded RNA binding [ISO]
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.711 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID