BAIT
CTNND2
Catnd2, Nprap, neurojugin
catenin (cadherin associated protein), delta 2
GO Process (3)
GO Function (0)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Cellular Component
Mus musculus
PREY
MAGI2
AIP-1, Acvri1, Acvrinp1, Acvrip1, Magi-2, S-SCAM, mKIAA0705
membrane associated guanylate kinase, WW and PDZ domain containing 2
GO Process (15)
GO Function (9)
GO Component (11)
Gene Ontology Biological Process
- SMAD protein signal transduction [IDA]
- cellular response to nerve growth factor stimulus [ISO]
- cytoplasmic transport [ISO]
- mitotic cell cycle arrest [ISO]
- negative regulation of activin receptor signaling pathway [IDA]
- negative regulation of cell migration [ISO]
- negative regulation of cell proliferation [ISO]
- negative regulation of protein kinase B signaling [ISO]
- nerve growth factor signaling pathway [ISO]
- positive regulation of neuron projection development [ISO]
- positive regulation of phosphoprotein phosphatase activity [ISO]
- positive regulation of receptor internalization [ISO]
- protein heterooligomerization [ISO]
- receptor clustering [ISO]
- signal transduction [IPI]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.827 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID