BAIT
EIF4B
2310046H11Rik, AL024095, C85189, Eif4a2
eukaryotic translation initiation factor 4B
GO Process (0)
GO Function (1)
GO Component (0)
Gene Ontology Molecular Function
Mus musculus
PREY
MTM1
AF073996, Mtm, mKIAA4176, RP23-300F6.3
X-linked myotubular myopathy gene 1
GO Process (8)
GO Function (6)
GO Component (8)
Gene Ontology Biological Process
- endosome to lysosome transport [ISO]
- intermediate filament organization [ISO]
- mitochondrion distribution [IMP, ISO]
- mitochondrion morphogenesis [IMP, ISO]
- muscle cell cellular homeostasis [IMP]
- phosphatidylinositol dephosphorylation [ISO]
- protein dephosphorylation [ISO]
- regulation of vacuole organization [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.7485 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID