BAIT
ATP6V1A
AI647066, Atp6a1, Atp6a2, Atp6v1a1, VA68, VPP2
ATPase, H+ transporting, lysosomal V1 subunit A
GO Process (0)
GO Function (0)
GO Component (8)
Gene Ontology Cellular Component
Mus musculus
PREY
MTPN
5033418D15Rik, Gcdp, V1
myotrophin
GO Process (7)
GO Function (0)
GO Component (6)
Gene Ontology Biological Process
- cell growth [ISO]
- positive regulation of NF-kappaB transcription factor activity [ISO]
- positive regulation of cardiac muscle hypertrophy [ISO]
- positive regulation of cell growth [ISO]
- positive regulation of macromolecule biosynthetic process [ISO]
- positive regulation of protein metabolic process [ISO]
- regulation of barbed-end actin filament capping [ISO]
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.7085 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID