BAIT
PRDX3
AW822249, Aop1, D0Tohi1, Ef2l, Mer5, Prx3, SP22, TDXM
peroxiredoxin 3
GO Process (17)
GO Function (6)
GO Component (7)
Gene Ontology Biological Process
- cellular response to oxidative stress [ISO]
- cellular response to reactive oxygen species [ISO]
- hydrogen peroxide catabolic process [ISO]
- maternal placenta development [IMP]
- mitochondrion organization [ISO]
- myeloid cell differentiation [IMP]
- negative regulation of apoptotic process [ISO]
- negative regulation of cysteine-type endopeptidase activity involved in apoptotic process [ISO]
- negative regulation of kinase activity [ISO]
- negative regulation of neuron apoptotic process [ISO]
- peptidyl-cysteine oxidation [ISO]
- positive regulation of NF-kappaB transcription factor activity [ISO]
- positive regulation of cell proliferation [ISO]
- regulation of mitochondrial membrane potential [ISO]
- response to hydrogen peroxide [ISO]
- response to lipopolysaccharide [IMP]
- response to oxidative stress [IMP, ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
NDUFS3
0610010M09Rik, CI-30kD, RP23-147D3.3
NADH dehydrogenase (ubiquinone) Fe-S protein 3
GO Process (4)
GO Function (1)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.712 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID