BAIT
NFASC
AA387016, D430023G06Rik, NF, mKIAA0756
neurofascin
GO Process (9)
GO Function (3)
GO Component (11)
Gene Ontology Biological Process
- axon guidance [IDA]
- clustering of voltage-gated sodium channels [IMP]
- heterotypic cell-cell adhesion [IGI]
- paranodal junction assembly [IMP]
- protein localization to juxtaparanode region of axon [IMP]
- protein localization to paranode region of axon [IMP]
- protein targeting to plasma membrane [ISO]
- synapse organization [IMP]
- transmission of nerve impulse [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
NRCAM
Bravo, C030017F07Rik, C130076O07Rik, mKIAA0343
neuronal cell adhesion molecule
GO Process (9)
GO Function (3)
GO Component (4)
Gene Ontology Biological Process
- axon guidance [IDA]
- central nervous system development [IDA]
- clustering of voltage-gated sodium channels [IMP, ISO]
- heterotypic cell-cell adhesion [IGI]
- neuronal action potential propagation [IMP]
- protein localization [IDA]
- regulation of neuron projection development [IMP]
- retinal ganglion cell axon guidance [IMP]
- single organismal cell-cell adhesion [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.795 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID