BAIT
RABGGTB
Rab geranylgeranyl transferase, b subunit
GO Process (1)
GO Function (3)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Mus musculus
PREY
PALM
paralemmin
GO Process (11)
GO Function (1)
GO Component (14)
Gene Ontology Biological Process
- cellular response to electrical stimulus [IDA]
- cytoskeleton organization [IDA]
- negative regulation of adenylate cyclase activity [IDA, ISO]
- negative regulation of cAMP biosynthetic process [IDA]
- negative regulation of dopamine receptor signaling pathway [ISO]
- positive regulation of dendritic spine development [IDA]
- positive regulation of filopodium assembly [IDA, ISO]
- protein localization [IDA]
- protein targeting to plasma membrane [IDA]
- regulation of cell shape [IDA]
- synapse maturation [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- apicolateral plasma membrane [ISO]
- axon [ISO]
- basolateral plasma membrane [ISO]
- cytoplasm [IDA]
- dendrite membrane [ISO]
- dendritic spine membrane [ISO]
- filopodium [IDA]
- filopodium membrane [ISO]
- intracellular membrane-bounded organelle [ISO]
- neuron spine [IDA]
- neuronal postsynaptic density [IDA]
- nucleoplasm [ISO]
- nucleus [ISO]
- plasma membrane [IDA, ISO]
Mus musculus
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain.
Connectivity webs mediate the unique biology of the mammalian brain. Yet, while cell circuit maps are increasingly available, knowledge of their underlying molecular networks remains limited. Here, we applied multi-dimensional biochemical fractionation with mass spectrometry and machine learning to survey endogenous macromolecules across the adult mouse brain. We defined a global "interactome" comprising over one thousand multi-protein complexes. These include ... [more]
Cell Syst Apr. 22, 2020; 10(4);333-350.e14 [Pubmed: 32325033]
Quantitative Score
- 0.753 [EPIC Score]
Throughput
- High Throughput
Additional Notes
- High confidence interactions had an EPIC Score >= 0.683
Curated By
- BioGRID